A new class of drugs known as selective serotonin reuptake inhibitors (SSRIs) are approved for the treatment of major depressive disorder (MDD) in post-menopausal women.
SSRIs such as sertraline (Zoloft), escitalopram (Celexa), fluoxetine (Prozac), paroxetine (Paxil), and citalopram (Celexa) have shown efficacy in clinical trials for a number of indications. These drugs work by increasing the levels of serotonin in the brain, a chemical that helps to increase mood and reduce feelings of anxiety. This mechanism is called serotonin reuptake. SSRIs work by stopping the reabsorption of serotonin in the brain.
These drugs are available by prescription only. They are not approved for use in children and adolescents and should only be taken under the supervision and prescription of a healthcare provider.
SSRIs are approved for use in patients with MDD who have been diagnosed with depression. MDD is defined as a major depressive episode in which the patient is at a significant level of distress and is clinically in remission. MDD is also described as an acute, relapsing, or recurring depression that can last for weeks to months. There are no data on the effectiveness of SSRIs in treating depression.
The first FDA-approved SSRI, fluoxetine (Prozac), was approved in 1992 for the treatment of MDD in the post-menopausal population. Since then, it has been approved for other indications. SSRIs, like sertraline (Zoloft), citalopram (Celexa), and paroxetine (Paxil), have shown efficacy in clinical trials for depression.
Although these drugs are generally well-tolerated, some patients may experience side effects. These side effects include:
The side effects of SSRIs have been listed in the following lists:
These side effects are usually reversible with continued use. However, in some patients, SSRIs may cause a worsening of symptoms. This is a very rare side effect. Therefore, if you experience any severe or persistent side effects, contact your healthcare provider immediately.
SSRIs have also been shown to be helpful in the treatment of anxiety disorders in adults. The drugs are FDA-approved to treat depression, generalized anxiety disorder (GAD), and obsessive-compulsive disorder (OCD). They are available as tablets, capsules, and liquids.
Some SSRIs are available over the counter without a prescription. However, the Food and Drug Administration (FDA) has approved only one drug in the class of SSRIs and that is Seroquel (quetiapine).
Because these drugs have been shown to be effective in treating depression, they should be used with caution in patients with a family history of MDD.
SSRIs should be prescribed in conjunction with a healthy diet and exercise. The risk of side effects with this drug may be greater in patients with a family history of depression.
The side effects of this drug may be more easily managed by monitoring these patients for the symptoms of depression.
ReferencesProduct InformationProduct name:Seroquel XR (quetiapine fumarate) belongs to a group of drugs called atypical antipsychotics. It works by changing the levels of a chemical called serotonin, which is involved in mood and behavior. Seroquel XR is available as a generic drug.
Seroquel XR (quetiapine fumarate) works by stopping the reabsorption of serotonin in the brain. This is done by increasing the amount of serotonin in the brain. Seroquel XR has been approved by the FDA for the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and obsessive-compulsive disorder (OCD).
Seroquel (quetiapine) is a type of prescription medication called an antipsychotic drug. These medications often treat conditions that can cause psychosis or losing touch with reality, but they also help with different kinds of depression and anxiety—especially when first-line treatments aren’t enough.
There are two types of antipsychotic drugs. “Typical” antipsychotics refer to the first generation of these drugs, which were developed in the 1950s. “Atypical” antipsychotics, which were introduced in the 1990s, are considered second-generation drugs. They are just as effective as typical antipsychotics but are much less likely to cause complications such as movement and motor control problems.
Seroquel (quetiapine) is an atypical antipsychotic. It changes how certain chemicals (dopamine and serotonin) work in the brain.
Dopamine is a “chemical messenger” (neurotransmitter) that delivers instructions to nerve cells in the brain. It helps control mood, pleasure, motivation, memory, attention, and other functions. Serotonin is also a chemical messenger. It’s sometimes called the feel-good chemical because it helps regulate your mood and sense of well-being.
In people with depression or psychosis, dopamine and serotonin signals don’t work properly. Seroquel (quetiapine) works by blocking these abnormal signals.
Typical antipsychotics:First-generation antipsychotics, like quetiapine, are usually second-generation. They have a lower risk of making these signals but are much less likely to do so. Second-generation antipsychotics are usually more effective than first-generation medications. They are also slightly more likely to cause withdrawal symptoms and to have higher rates of metabolic side effects, such as weight gain and type 2 diabetes.
Seroquel (quetiapine) is available in a 250-milligram (mg) tablet. You take it 1 to 3 hours before sexual activity. If you take it more than 3 hours before sexual activity, you should stop taking it and see your health care provider immediately.
Seroquel (quetiapine) should not be taken with any other medications or supplements. You should talk to your health care provider about the risks and benefits of taking this medication before starting any other medication. This medication may raise certain dangerous side effects, such as selective serotonin reuptake inhibitors (SSRIs), which can cause a person with a new antipsychotic to have sudden, uncontrollable changes in one’s speech, behavior, or thinking.
It’s important to keep in mind that not all antipsychotics are safe for you. You and your health care provider should talk about any concerns you have about taking this medication.
Typical antipsychotic: How this drug worksIt is used to treat conditions such as depression, psychosis, and losing touch with reality, among many other conditions.
It helps to better understand how certain chemicals (dopamine and serotonin) work in the brain. When certain chemicals (dopamine and serotonin) are hyperactive (produced by cells in the brain), they can’t produce enough information to cause serious problems like movement or motor control. This causes psychosis, which is the inability to concentrate or focus on a task.
It doesn’t block dopamine signals. Instead, it helps to lower them.
Dopamine and serotonin tell dopamine and serotonin not to work. Seroquel (quetiapine) causes a jump in serotonin levels. Seroquel (quetiapine) also raises dopamine and/or serotonin levels. Some people with depression or psychosis also have increased dopamine and/or serotonin levels.
Dopamine and serotonin signals don’t work when hyperactive dopamine and/or serotonin are produced by the brain. They don’t cause movement or motor problems. Seroquel (quetiapine) helps to lower hyperactive- serotonin signals.
Seroquel (quetiapine) raises serotonin and dopamine levels.
Dopamine and/or serotonin are released by the cells in the brain. Seroquel (quetiapine) helps to release these chemicals.
No. People do it, but getting it through Customs without it being confiscated depends on which agent interviews you upon arrival back in the US.
The Food and Drug Administration policy on theimportation of prescription drugspurchased abroad is fairly clear.
Under most circumstances,federal guidelines prohibit the importation of such drugs for personal use, largely because medications sold in another country have not been approved by the FDA for use in this country.
That said, your personal experience in returning to the United States with or another prescription drug you’ve purchased abroad depends to a very large extent on the Customs agent who checks your baggage upon your return.
If you’ve been honest in filling out your Customs declaration and have listed the foreign-bought medications, Customs legally could seize the drugs. However, the tendency is to look the other way if the drug in question is not a controlled substance and if the amount purchased doesn’t exceed a 90-day supply.
do allow thepersonal importation of prescription drugs that treat serious medical conditionsand that aren’t available in the United States.
However, there are a few other conditions that govern the policy on such drugs.
The FDA’s guidelines apply toprescription medications that are brought in from any country outside the United States, including Canada.
While most over-the-counter medications can be imported in amounts consistent with personal use, this policy does not extend to products that are OTC in other countries but available only by prescription in the United States.
The bottom line: Be aware that you’re running arisk of confiscation when you return to the United States with prescription drugsbought abroad.
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Generic versions of atypical antipsychotics like olanzapine (Zyprexa) and risperidone (Risperdal) are available in the United States. There are a number of generic versions of these drugs available in the U. S. including the brand-name drugs, quetiapine (Seroquel) and atypical antipsychotics, which are approved in the U. for the treatment of schizophrenia. QATRID is available for the treatment of schizophrenia. It is available in the U. from pharmacies that are not listed on the product label.
QATRID is a generic version of the antipsychotics that are approved by the FDA to treat both schizophrenia and major depressive disorder. QATRID has been approved by the FDA for more than three decades to treat both schizophrenia and bipolar disorder. QATRID is also used to treat obsessive compulsive disorder, a condition that affects around 40% of American adults, with an estimated 300 million Americans taking these drugs. QATRID has been approved for the treatment of bipolar disorder.
The brand-name drugs atypical antipsychotics like quetiapine (Seroquel) and risperidone (Risperdal) are approved by the FDA for the treatment of schizophrenia and major depressive disorder. The brand-name drugs are also approved to treat the following conditions:
The brand-name drugs were first approved by the FDA in 1992. In 2004, the Food and Drug Administration approved the brand-name drugs in the U. and has been available over the counter since 2004.
The brand-name drugs are available in various forms that are approved by the FDA to treat both schizophrenia and bipolar disorder. Some of the generic versions of these drugs include:
It is also used to treat a condition called major depressive disorder. The brand-name drugs are also approved to treat bipolar disorder. QATRID is also available in the U.
The brand-name drugs are available in various brand-name formulations, including:
In addition to the brand-name drugs, there are generic versions of these drugs that are approved to treat both schizophrenia and bipolar disorder. The following are the common brand-name drugs approved by the FDA to treat both schizophrenia and bipolar disorder:
The following are the common brand-name drugs approved by the FDA to treat schizophrenia and bipolar disorder:
The following are the common brand-name drugs approved by the FDA to treat schizophrenia:
The following are the common brand-name drugs approved by the FDA to treat bipolar disorder:
The brand-name drugs are available in brand-name formulations.
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